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Dr. Harrell’s Collection of Peer
Reviewed Scientific White Papers

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(2023) 

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  1. Harrell CR, Feulner L, Djonov V, Pavlovic D, Volarevic V. The Molecular Mechanisms Responsible for Tear Hyperosmolarity-Induced Pathological Changes in the Eyes of Dry Eye Disease Patients. Cells. 2023; Publisher/Web Link 

  2. Harrell CR, Djonov V, Antonijevic A, Volarevic V. (2023) NLRP3 Inflammasome as a Potentially New Therapeutic Target of Mesenchymal Stem Cells and Their Exosomes in the Treatment of Inflammatory Eye Diseases. Cells. 2023, 12, 2327. DOI:Publisher/Web Link   

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(2019) 

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  1. Harrell CR, Jovicic N, Djonov V, Arsenijevic N, Volarevic V. (2019) Mesenchymal Stem Cell- Derived Exosomes and Other Extracellular Vesicles as New Remedies in the Therapy of Inflammatory Diseases. Cells. 2019;8(12):1605. DOI:Publisher/Web Link  

  2. ​Volarevic V, Zdravkovic N, Harrell CR, et al. (2019) Galectin-3 Regulates Indoleamine-2,3- dioxygenase-Dependent Cross-Talk between Colon-Infiltrating Dendritic Cells and T Regulatory Cells and May Represent a Valuable Biomarker for Monitoring the Progression of Ulcerative Colitis. Cells. 2019;8(7):709. DOI:Publisher/Web Link 

  3. Harrell CR, Fellabaum C, Jovicic N, Djonov V, Arsenijevic N, Volarevic V. (2019) Molecular Mechanisms Responsible for Therapeutic Potential of Mesenchymal Stem Cell-Derived Secretome. Cells. 2019;8(5):467. DOI: Publisher/Web Link 

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(2023) 

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  1. Harrell CR, Djonov V, Volarevic A, et al. (2023) The role of mesenchymal stem cell-derived exosomes in tumor progression. Biocell; 2023 47(8): 1757-1769. DOI:  Publisher/Web Link 

 

(2021) 

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  1. Harrell CR, Volaravic A, Pavlovic D, Djonov V, Volarevic V. (2021) Mesenchymal stem cell- derived exosomes as new remedy for the treatment of inflammatory eye diseases. Biocell; DOI: Publisher/Web Link  

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2023)

 

  1. Pavlovic D, Miloradovic D, Stojanovic MD, Harrell CR, et al. (2023) Cigarette smoke attenuates mesenchymal stem cell-based suppression of immune cell-driven acute liver failure. Toxicology Letters. 2023 Aug;385:12-20. DOI: Publisher/Web Link   

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(2023) 

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  1. Harrell CR, Djonov V, Volarevic V. (2023) Mesenchymal stem cell-derived microRNAs: Friends or foes of tumor cells? Histology and Histopathology. 2023; DOI: Publisher/Web Link  

 

(2022) 

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  1. Harrell CR, Djonov V, Volaravic V. (2022) The effects of cigarette smoking and nicotine on the therapeutic potential of mesenchymal stem cells. Histology and Histopathology. 2022;(37):93- 100 DOI: Publisher/Web Link  

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(2023)

 

  1. Harrell CR. (2023) Regener-Eyes® Ophthalmic Solution: A New Therapeutic Agent to Relieve Dryness of the Eye for Tear Hyperosmolarity-Induced Pathological Changes in the Eyes of Patients Suffering from Dry Eye Discomfort. Austin Journal of Clinical Ophthalmology. Publisher/Web Link Article  

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(2022) 

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  1. Harrell CR, Jakovljevic V, Volarevic V, Zdravkovic M, Djonov V. (2023) Molecular Mechanisms Responsible for Mesenchymal Stem Cell-Based Modulation of Obstructive Sleep Apnea. International Journal of Molecular Sciences. February 2023; 24(4):3708. DOI: Publisher/Web Link  

  2. Harrell CR. (2022) Therapeutic Potential of d-MAPPS™ for Ocular Inflammatory Diseases and Regeneration of Injured Corneal and Retinal Tissue. International Journal of Molecular Sciences. 2022; 23(21):13528. DOI: Publisher/Web Link 

  3. Harrell CR, Djonov V, Volarevic V. (2022) Therapeutic Potential of Mesenchymal Stem Cells in the Treatment of Ocular Graft-Versus-Host Disease. International Journal of Molecular Sciences. 2022; 23(21):13254. DOI: Publisher/Web Link  

  4. Harrell CR, Volarevic V, Djonov V, Volarevic A. (2022) Therapeutic Potential of Exosomes Derived from Adipose Tissue-Sourced Mesenchymal Stem Cells in the Treatment of Neural and Retinal Diseases. International Journal of Molecular Sciences. 2022;23(9):4487. DOI: Publisher/Web Link  

 

(2021)

 

  1. Harrell CR, Volarevic A, Djonov VG, Jovicic N, Volarevic V. (2021) Mesenchymal Stem Cell: A Friend or Foe in Anti-Tumor Immunity. International Journal of Molecular Sciences. 2021;22(22):12429. DOI: Publisher/Web Link  

  2. Harrell CR, Djonov V, Volarevic V. (2021) The Cross-talk between Mesenchymal Stem Cells and Immune Cells in Tissue Repair and Regeneration. International Journal of Molecular Sciences. 2021;22(5):2472. DOI: Publisher/Web Link 

  3. Harrell CR, Volarevic A, Djonov V, Volarevic V. (2021) Mesenchymal Stem Cell-Derived Exosomes as New Remedy for the Treatment of Neurocognitive Disorders. International Journal of Molecular Sciences. 2021;22(3):1433. DOI: Publsher/Web Link  

 

(2018) 

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  1. Gazdic M, Volarevic V, Harrell CR, et al. (2018) Stem Cells Therapy for Spinal Cord Injury. International Journal of Molecular Sciences. 2018;19(4):1039. doi: Publisher/Web Link  

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(2022) 

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  1. Harrell CR, Pavlovic D, Djonov V, Volarevic V. (2022) Therapeutic potential of mesenchymal stem cells in the treatment of acute liver failure. World J Gastroenterol. 2022;28(28):3627-3636. DOI: Publisher/Web Link   

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(2023) 

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  1. Harrell CR, Volaveric V. (2023) Restoration of Meibomian Gland Functionality with Novel Mesenchymal Stem Cell-Derived Product “Derived-Multiple Allogeneic Proteins Paracrine Signaling (d-MAPPS)”: A Case Report. Experimental and Applied Biomedical Research. June 2023; 24(2):169-174. DOI: Publisher/Web Link 

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(2022) 

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  1. Harrell CR, Fellabaum C, Miloradovic D, et al. (2022) Therapeutic Potential of Derived-Multiple Allogeneic Proteins Paracrine Signaling-D-Mapps” in the Treatment of Dry Eye Disease. Serbian Journal of Experimental and Clinical Research. 2022;0(0). DOI: Publisher/Web Link 

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(2019) 

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  1. Harrell CR, Markovic BS, Fellabaum C, et al. (2019) Exo-D-MAPPS Attenuates Production of Inflammatory Cytokines and Promoted Generation of Immunosuppressive Phenotype in Peripheral Blood Mononuclear Cells. Serbian Journal of Experimental and Clinical Research. 2019;0(0). DOI: Publisher/Web Link  

  2. ​Djokovic B, Jankovic MG, Harrell CR, Fellabaum C, Arsenijevic N, Volarevic V. (2019) New Insights in the Pathogenesis of Cisplatin-Induced Nephrotoxicity. Serbian Journal of Experimental and Clinical Research. 2019;0(0). DOI:  Publisher/Web Link 

  3. Harrell CR, Fellabaum C, Markovic BS, Arsenijevic A, Volarevic V. (2019) Therapeutic Potential of Exosomes Derived Multiple Allogeneic Proteins Paracrine Signaling: Exosomes d-MAPPS” is Based on the Effects of Exosomes, Immunosuppressive and Trophic Factors. Serbian Journal of Experimental and Clinical Research. 2019;20(3):189-197. DOI: Publisher/Web Link  

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(2018) 

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  1. Miloradovic D, Miloradovic D, Harrell CR, et al. (2018) Mesenchymal Stem Cells Attenuate Acute Liver Failure by Promoting Expansion of Regulatory T Cells in an Indoleamine 2,3- Dioxygenase-Dependent Manner. Serbian Journal of Experimental and Clinical Research. 2020;21(3):257-262. Doi: Publisher/Web Link 

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Analytical Cellular Pathology

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(2022)

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  1. Harrell CR, Pavlovic D, Miloradovic D, et al. (2022) “Derived Multiple Allogeneic Protein Paracrine Signaling (d-MAPPS)” Enhances T Cell-Driven Immune Response to Murine Mammary Carcinoma. Analytical Cellular Pathology. DOI:  Publisher/Web Link  

 

(2020)

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  1. Harrell CR, Jovicic BP, Djonov V, Volarevic V. (2020) Therapeutic Potential of Mesenchymal Stem Cells and Their Secretome in the Treatment of SARS-CoV-2-Induced Acute Respiratory Distress Syndrome. Amantini C, ed. Analytical Cellular Pathology. 2020;2020:1-11. DOI: Publisher/Web Link  

  2. Harrell CR, Miloradovic D, Sadikot R, et al. (2020) Molecular and Cellular Mechanisms Responsible for Beneficial Effects of Mesenchymal Stem Cell-Derived Product “Exo-d- MAPPS” in Attenuation of Chronic Airway Inflammation. Analytical Cellular Pathology. 2020;2020:1-15. DOI: Publisher/Web Link  

 

(2017)

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  1. Harrell CR, Arsenijevic A, Fellabaum C, Volarevic V. (2017) Mesenchymal Stem Cells as New Therapeutic Agents for the Treatment of Primary Biliary Cholangitis. Analytical cellular pathology (Amsterdam) 2017(3):1-9. DOI: Publisher/Web Link   

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Stem Cells International

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(2020)

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  1. Miloradovic D, Harrell CR, Djonov V, Arsenijevic N, Volarevic V. (2020) The Effects of Mesenchymal Stem Cells on Antimelanoma Immunity Depend on the Timing of Their Administration. Stem Cells International. 2020;2020:1-13. DOI: Publisher/Web Link  

 

(2019)

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  1. Harrell CR, Fellabaum C, Arsenijevic A, Markovic BS, Djonov V, Volarevic V. (2019) Therapeutic Potential of Mesenchymal Stem Cells and Their Secretome in the Treatment of Glaucoma. Stem Cells International. 2019;2019:1-11. DOI: Publisher/Web Link  

  2. Harrell CR, Sadikot R, Pascual J, et al. (2019) Mesenchymal Stem Cell-Based Therapy of Inflammatory Lung Diseases: Current Understanding and Future Perspectives. Stem Cells International. 2019;2019:1-14. doi: Publisher/Web Link

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(2022)

 

  1. Harrell CR, Jovicic N, Djonov V, Volarevic V. (2022) Therapeutic Use of Mesenchymal Stem Cell-Derived Exosomes: From Basic Science to Clinics. Pharmaceutics. 2020;12(5):474. DOI:  Publisher/Web Link  

 

(2021)

 

  1. Harrell CR, Jovicic BP, Djonov V, Volarevic V. (2021) Molecular Mechanisms Responsible for Mesenchymal Stem Cell-Based Treatment of Viral Diseases. Pathogens. 2021;10(4):409. DOI: Publisher/Web Link  

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(2021)

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  1. Harrell CR, McDonald M. (2021) Therapeutic Potential of Regener-Eyes Ophthalmic Solution. EYEWORLD. Published online July 16, 2021. DOI: Publisher/Web Link  

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(2020) 

  1. Harrell CR, Markovic BS, Fellabaum C, Arsenijevic N, Djonov V, Volarevic V. (2020) The role of Interleukin 1 receptor antagonist in mesenchymal stem cell-based tissue repair and regeneration. BioFactors. 2020;46(2):263-275. DOI: Publisher/Web Link    

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(2019)

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  1. Volarevic V, Markovic BS, Harrell CR, et al. (2019) Galectin 3 protects from cisplatin-induced acute kidney injury by promoting TLR-2-dependent activation of IDO1/Kynurenine pathway in renal DCs. Theranostics. 2019;9(20):5976-6001. DOI: Publisher/Web Link     

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(2019)

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  1. Volarevic V, Djokovic B, Harrell CR, et al. (2019) Molecular mechanisms of cisplatin-induced nephrotoxicity: a balance on the knife edge between renoprotection and tumor toxicity. Journal of Biomedical Science. 2019;26(1):25. doi:  Publisher/Web Link      

 

(2018) 

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  1. Harrell CR, Markovic BS, Fellabaum C, Arsenijevic A, Djonov V, Volarevic V. (2018) Molecular mechanisms underlying therapeutic potential of pericytes. Journal of Biomedical Science. 2018;25(1). Doi: Publisher/Web Link  

(2019)

 

  1. Harrell CR, Markovic BS, Fellabaum C, Arsenijevic A, Volarevic V. (2019) Mesenchymal stem cell-based therapy of osteoarthritis: Current knowledge and future perspectives. Biomedicine & Pharmacotherapy. 2019;109:2318-2326. doi: Publisher/Web Link       

 

(2018)

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  1. Jakovljevic J, Harrell CR, Fellabaum C, Arsenijevic A, Jovicic N, Volarevic V. (2018) Modulation of autophagy as new approach in mesenchymal stem cell-based therapy. Biomedicine & Pharmacotherapy. 2018;104:404-410. Doi: Publisher/Web Link 

  2. Gazdic M, Markovic BS, Harrell CR, et al. (2018) Crosstalk between mesenchymal stem cells and T regulatory cells is crucially important for the attenuation of acute liver injury. Liver Transplantation. 2018;24(5):687-702. doi: Publisher/Web Link  

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(2019)

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  1. Harrell CR, Gazdic M, Fellabaum C, et al. (2019) Therapeutic Potential of Amniotic Fluid Derived Mesenchymal Stem Cells Based on their Differentiation Capacity and Immunomodulatory Properties. Current Stem Cell Research & Therapy. 2019;14(4):327-336. doi: Publisher/Web Link  

(2018)

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  1. Acovic A, Gazdic M, Harrell CR, Fellabaum C, Arsenijevic N, Volarevic V. (2018) Role of indoleamine 2,3-dioxygenase in pathology of the gastrointestinal tract. Therapeutic Advances in Gastroenterology. 2018;11:175628481881533. doi: Publisher/Web Link  

  2. Acovic A, Markovic BS, Harrell CR, et al. (2018) Indoleamine 2,3-dioxygenase-dependent expansion of T-regulatory cells maintains mucosal healing in ulcerative colitis. Therapeutic Advances in Gastroenterology. 2018;11:175628481879355. Doi: Publisher/Web Link  

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(2018)

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  1. Gazdic M, Markovic BS, Harrell CR, et al. (2018) Crosstalk between mesenchymal stem cells and T regulatory cells is crucially important for the attenuation of acute liver injury. Liver Transplantation. 2018;24(5):687-702. doi: Publisher/Web Link  

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(2018)

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  1. MarKanjevac T, Harrell CR, et al. (2018) Molecular and Cellular Mechanisms Involved in Mesenchymal Stem Cell-Based Therapy of Inflammatory Bowel Diseases. Stem Cell Reviews and Reports. 2018;14(2):153-165. doi: Publisher/Web Link   

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(2018)

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  1. Harrell CR, Djonov V, Fellabaum C, Volarevic V. (2018) Risks of Using Sterilization by Gamma Radiation: The Other Side of the Coin. International Journal of Medical Sciences. 2018;15(3):274-279. DOI: Publisher/Web Link   

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(1994)

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  1. 9Spira M, Liu B, Xu Z, Harrell CR, Chahadeh H. (1994) Human amnion collagen for soft tissue augmentation—biochemical characterizations and animal observations. Journal of Biomedical Materials Research. 1994;28(1):91-96. doi: Publisher/Web Link  

 

(1989)

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  1. Liu B, Harrell CR, Davis RH, Dresden MH, Spira M. (1989) The effect of gamma irradiation on injectable human amnion collagen. Journal of Biomedical Materials Research. 1989;23(8):833- 844. DOI: Publisher/Web Link  

(1992) 

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  1. Harrell CR. (1992) Enhancement of radiation-induced cell killing, and DNA double-strand breaks in a human tumor cell line using nanomolar concentrations of aclacinomycin A. Radiation research. Published online 1992. doi:  Publisher/Web Link  

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(1989)

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  1. Liu B, Harrell CR, Lamb DJ, Dresden MH, Spira M. (1989) The growth of human fibroblasts and A431 epidermoid carcinoma cells on gamma-irradiated human amnion collagen substrata. Experientia. 1989;45(10):1002-1006. doi: Publisher/Web Link 

 

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(1989)

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  1. Harrell CR. (1989) Immune response to gamma-irradiated injectable human amnion and human skin collagens in the rat. Archives of dermatology. Published online August 1989. doi: Publisher/Web Link  

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